Table 1 GO enrichment for the genes in the coexpression modules of glioma
Module | Term | Count | % | PValue |
|---|---|---|---|---|
M1 | GO:0006915~apoptotic process | 87 | 4.71 | 2.40E-05 |
GO:0015031~protein transport | 66 | 3.57 | 1.90E-05 | |
GO:0006412~translation | 63 | 3.41 | 5.96E-12 | |
GO:0098609~cell-cell adhesion | 62 | 3.35 | 3.69E-10 | |
GO:0051301~cell division | 56 | 3.03 | 2.74E-04 | |
M2 | GO:0006915~apoptotic process | 42 | 5.12 | 0.001513 |
GO:0006412~translation | 41 | 5.00 | 2.32E-12 | |
GO:0006413~translational initiation | 36 | 4.39 | 1.28E-17 | |
GO:0000398~mRNA splicing, via spliceosome | 35 | 4.27 | 2.54E-10 | |
GO:0016032~viral process | 35 | 4.27 | 4.94E-07 | |
M3 | GO:0045087~innate immune response | 19 | 6.11 | 6.26E-04 |
GO:0098609~cell-cell adhesion | 15 | 4.82 | 3.26E-04 | |
GO:0006886~intracellular protein transport | 13 | 4.18 | 9.88E-04 | |
GO:0050900~leukocyte migration | 12 | 3.86 | 1.02E-05 | |
GO:0008360~regulation of cell shape | 12 | 3.86 | 3.72E-05 | |
M4 | GO:0007165~signal transduction | 46 | 15.23 | 5.41E-08 |
GO:0006954~inflammatory response | 33 | 10.93 | 2.59E-14 | |
GO:0045087~innate immune response | 24 | 7.95 | 6.95E-07 | |
GO:0006955~immune response | 20 | 6.62 | 6.90E-05 | |
GO:0006915~apoptotic process | 20 | 6.62 | 0.002587 | |
M6 | GO:0000398~mRNA splicing, via spliceosome | 9 | 5.49 | 5.01E-04 |
GO:0035556~intracellular signal transduction | 9 | 5.49 | 0.0183 | |
GO:0006357~regulation of transcription from RNA polymerase II promoter | 9 | 5.49 | 0.029314 | |
GO:0006397~mRNA processing | 8 | 4.88 | 6.98E-04 | |
GO:0015031~protein transport | 8 | 4.88 | 0.044714 | |
M7 | GO:0006915~apoptotic process | 12 | 7.64 | 0.00608 |
GO:0043066~negative regulation of apoptotic process | 10 | 6.37 | 0.011294 | |
GO:0007264~small GTPase mediated signal transduction | 9 | 5.73 | 8.48E-04 | |
GO:0042981~regulation of apoptotic process | 6 | 3.82 | 0.028884 | |
GO:0002223~stimulatory C-type lectin receptor signaling pathway | 5 | 3.18 | 0.010221 | |
M8 | GO:0051607~defense response to virus | 31 | 19.87 | 6.03E-32 |
GO:0060337~type I interferon signaling pathway | 24 | 15.38 | 3.00E-32 | |
GO:0045087~innate immune response | 21 | 13.46 | 5.29E-10 | |
GO:0009615~response to virus | 19 | 12.18 | 1.42E-18 | |
GO:0045944~positive regulation of transcription from RNA polymerase II promoter | 18 | 11.54 | 0.003564 |