Table 4 Results of meta analysis on the association between IL-18 gene, IL-18 level and CAD
Number of included references | Total number of participants | Case | Control | Heterogeneity | Effect size | |||
|---|---|---|---|---|---|---|---|---|
I2 | P values | OR/WMD | P values | |||||
-137G/C and CVDs | 12 | 4273 | 2596 | 1677 | 74.60% | < 0.05 | 0.722 (0.440, 1.183) | > 0.05 |
-607C/A and CVDs | 8 | 2202 | 1319 | 883 | 82.3% | < 0.05 | 0.726 (0.432, 1.218) | > 0.05 |
Level of IL-18 and CVDs | 4 | 2203 | 786 | 1417 | 96.1% | < 0.05 | 50.844 (33.455, 68.233) | < 0.05 |