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Table 4 Results of meta analysis on the association between IL-18 gene, IL-18 level and CAD

From: No association between interleukin-18 levels and risk of cardiovascular disease: A Mendelian randomization study

 Number of included referencesTotal number of participantsCaseControlHeterogeneityEffect size
I2P valuesOR/WMDP values
-137G/C and CVDs1242732596167774.60%< 0.050.722 (0.440, 1.183)> 0.05
-607C/A and CVDs82202131988382.3%< 0.050.726 (0.432, 1.218)> 0.05
Level of IL-18 and CVDs42203786141796.1%< 0.0550.844 (33.455, 68.233)< 0.05
  1. 50.844 pg/ml (95%CI =33.455–68.233