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Table 2 Basic characteristics of the included literature (IL 18 genetic variation and IL-18 level)

From: No association between interleukin-18 levels and risk of cardiovascular disease: A Mendelian randomization study

AuthoryearSample sizeIL-18 level(pg/ml)-137 G/CSample sizeIL-18 level(pg/ml)-607 C/ANOS score
(mean ± SD)(mean ± SD)
GGGCCCGGGCCCCCCAAACCCAAA
Opstad [16]201153239469248.44 ± 20.54245.41 ± 20.84271.43 ± 37.22364500132243.39 ± 21.02249.42 ± 20.34253.33 ± 32.377
Mitrokhin [17]2018867614145.40 ± 22.0994.44 ± 14.32107.18 ± 23.72569028117.08 ± 20.1286.00 ± 11.58106.96 ± 20.137
  1. NOS score: Newcastle-Ottawa Scale for Assessing the Quality of Nonrandomized Studies in Meta-Analysis, from 1 to 9