Fig. 3

The patient carries one heterozygous mutation, c.301 c > T, P. (Arg 101 Trp), in exon 3 of the IL-10RA gene, which is a missense mutation (a, arrow). Her father also carries one heterozygous mutation, c.301 c > T, P. (Arg 101 Trp), in exon 3 of the IL-10RA gene (b, arrow). Her mother has no abnormalities in this coding region of the IL-10RA gene (3-c)