Fig. 5

Overexpression of PKD-SE rescues the small eye phenotype of several L alleles. Typical examples of female heads are shown. (a-d) Upper row: Eye phenotype of the three homozygous Lobe alleles, L¹ (b), L⁵ (c), and L^G (d) in the background of UAS-PKD-SE, which does not affect the eye of the control y¹ w^67c23 (a). (a’-d’) Lower row: Overexpression of UAS-PKD-SE with ey-Gal4 (ey::PKD-SE) does not disturb outer eye morphology (a’), however, results in a rescue of the small eye of any tested L allele (b’-d’). (e) Quantification of eye phenotypes in the given genotype, using the following classification: c0, wild type eyes; c1, one eye is smaller; c2, both eyes are smaller; c3, one eye is smaller and one is of pinhead size or absent; c4 both eyes are of pinhead size or absent. Genotypes are depicted below each column; (+) indicates third chromosome normal for PKD. Fractions of phenotypes are depicted; numbers of assessed females are indicated in each column. The animals were derived from a cross of L*/CyO; ey-Gal4/TM3Sb x L*/CyO; UAS-PKD-SE/TM3Sb at 18 °C