Skip to main content
Fig. 2 | Hereditas

Fig. 2

From: Genetic interactions between Protein Kinase D and Lobe mutants during eye development of Drosophila melanogaster

Fig. 2

Genetic interaction of PKD with L2. Head of female flies; the left column shows a wild type OreR background (a), the right column a L2/+ heterozygous background (a’). PKD26 homozygotes have wild type eyes (b). Yet, lack of PKD strongly enhances the dominant L2 small eye phenotype (b’). Overexpression of UAS-PKD-SE in the developing eye with ey-Gal4 is itself without apparent phenotype (c), but rescues the small eye phenotype of L2/+ mutant flies (c’). (d) The dominant L2 eye phenotype is background-dependent and often varies between both eyes. For a quantitative analysis of the genetic interaction, the L2 eye phenotype was classified as follows: c0, wild type eyes; c1, one eye is smaller; c2, both eyes are smaller; c3, one eye is smaller and one is of pinhead size or absent; c4 both eyes are of pinhead size or absent. Genotypes are depicted below each column. The number of flies of the given genotype assessed in the experiment is indicated within each column. Note the strong enhancement of the L2 /+ phenotype by the absence of PKD and its rescue by overexpression of PKD-SE. Overexpression of PKD-WT had no impact, and that of PKD-kd caused little enhancement

Back to article page