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Table 1 Associations of the single-nucleotide polymorphisms rs2231142 in ABCG2 with the clinical features of the gout patients

From: ABCG2 gene polymorphism rs2231142 is associated with gout comorbidities but not allopurinol response in primary gout patients of a Chinese Han male population

Parameter Baseline (mean ± SEM) (1)GG (2)TG (3)TT (1)vs.(2)vs.(3) F/x2, P value Partialη2
Age 52.75 ± 12.88 52.74 ± 13.04 52.95 ± 12.77 52.35 ± 12.97 0.208,0.812 0.000
BMI (kg/m2) 27.16 ± 3.62 27.56 ± 3.58 27.07 ± 3.90 26.89 ± 3.03 2.765,0.063 0.005
SBP (mmHg) 137.53 ± 19.90 138.24 ± 19.21 137.13 ± 19.83 137.53 ± 20.79 0.289,0.749 0.001
DBP (mmHg) 89.48 ± 12.95 89.83 ± 12.62 89.10 ± 13.04 89.87 ± 13.13 0.450,0.638 0.001
FPG (mmol/L) 6.19 ± 1.70 6.18 ± 1.69 6.22 ± 1.77 6.11 ± 1.45 0.435,0.647 0.000
Triglyceride (mmol/L) 2.45 ± 2.20 2.49 ± 2.25 2.41 ± 2.22 2.38 ± 1.56 0.234,0.791 0.001
Total cholesterol (mmol/L) 5.25 ± 1.19 5.29 ± 1.14 5.21 ± 1.23 5.29 ± 1.14 0.641,0.527 0.001
SUA (μmol/L) 474.51 ± 111.37 466.37 ± 115.83* 464.58 ± 112.59* 496.99 ± 104.43 8.798,< 0.001 0.014
Urea nitrogen (mmol/L) 5.81 ± 2.83 5.80 ± 1.92 5.78 ± 3.07 5.93 ± 3.29 0.259,0.771 0.001
SCr (μmol/L) 90.75 ± 42.39 87.18 ± 24.90* 89.13 ± 31.42* 97.74 ± 67.69 5.400,0.005 0.010
  1. Data are the mean ± SEM. Statistical significance was defined as P < 0.05. Partial η2 is effect size. β = 0.2
  2. BMI body mass index, SBP systolic blood pressure. DBP diastolic blood pressure, FPG fasting plasma glucose, SUA serum uric acid, SCr serum creatinine