Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analyses

Table 5 Information of RNA-binding proteins of lncRNAs

Gene symbol	Gene title	Involved cell functions	References
EIF4B	eukaryotic initiation factor 4B	long-term plastic changes in neuron	[34]
PABPC1	cytoplasmic poly(A)-binding protein 1	inflammation	[35]
FUS	fused in sarcoma	motor neuron degeneration	[36]
Pum2	pumilio 2	neurogenesis	[37]
MBNL1	muscleblind-like protein 1	neuron development	[38]
ACO1	aconitase 1	neuron mitochondrial function	[39]
KHSRP	KH-type splicing regulatory protein	inflammation, neuron survival and growth	[40]
YTHDC1	YTH domain-containing protein 1	neuron development	[41]
SFRS9	SR-family splicing factor 9	neuronal stimulation	[42]
RBMX	RNA binding motif protein X-linked gene	neuron development	[43]
SFRS13A	SR-family splicing factor 13A	cholesterol homeostasis, AD risk	[44]
KHDRBS3	KH RNA binding domain containing, signal transduction associated 3	cell proliferation	[45]
ELAVL1	ELAV-like protein 1	neurogenesis, neuroprotection	[46, 47]
SFRS1	SR-family splicing factor 1	neuron differentiation and survival	[48, 49]

ISSN: 1601-5223