Table 3 Diagnostic accuracy based on serum miRNA levels
From: Identification of serum microRNAs as diagnostic biomarkers for schizophrenia
miRNAs | AUC | 95%CI | P-value | P-Bonferroni | Sensitivity | Specificity | Youden index J |
|---|---|---|---|---|---|---|---|
miR-34a-5p | 0.546 | 0.480~0.610 | 0.2392 | 3.3488 | 65% | 60% | 0.25 |
miR-432-5p | 0.764 | 0.706~0.817 | < 0.0001 | < 0.01 | 62.50% | 82.50% | 0.45 |
miR-449a | 0.598 | 0.533~0.661 | 0.008 | 0.112 | 60.00% | 65.00% | 0.25 |
miR-34a + miR-432-5p | 0.807 | 0.752~0.855 | < 0.0001 | < 0.01 | 97.50% | 55.00% | 0.525 |
miR-34a + miR-449a | 0.616 | 0.552~0.678 | 0.0014 | 0.0196 | 67.50% | 57.50% | 0.25 |
miR-432-5p + miR-449a | 0.841 | 0.789~0.885 | < 0.0001 | < 0.01 | 90.00% | 80.00% | 0.7 |
miR-34a + miR-432-5p + miR-449a | 0.843 | 0.791~0.887 | < 0.0001 | < 0.01 | 90.00% | 77.50% | 0.675 |