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Table 3 Diagnostic accuracy based on serum miRNA levels

From: Identification of serum microRNAs as diagnostic biomarkers for schizophrenia

miRNAs AUC 95%CI P-value P-Bonferroni Sensitivity Specificity Youden index J
miR-34a-5p 0.546 0.480~0.610 0.2392 3.3488 65% 60% 0.25
miR-432-5p 0.764 0.706~0.817 < 0.0001 < 0.01 62.50% 82.50% 0.45
miR-449a 0.598 0.533~0.661 0.008 0.112 60.00% 65.00% 0.25
miR-34a + miR-432-5p 0.807 0.752~0.855 < 0.0001 < 0.01 97.50% 55.00% 0.525
miR-34a + miR-449a 0.616 0.552~0.678 0.0014 0.0196 67.50% 57.50% 0.25
miR-432-5p + miR-449a 0.841 0.789~0.885 < 0.0001 < 0.01 90.00% 80.00% 0.7
miR-34a + miR-432-5p + miR-449a 0.843 0.791~0.887 < 0.0001 < 0.01 90.00% 77.50% 0.675