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Table 2 KEGG pathway enriched by differentially expressed genes in different modules

From: Differentially expressed genes between systemic sclerosis and rheumatoid arthritis

Term Description P-value Genes
Module1
 hsa04062 Chemokine signaling pathway 1.04E-08 PPBP;CXCL13;GNG12;GNG11;CXCL5;GNAI1
 hsa04726 Serotonergic synapse 2.68E-06 HTR5A;GNG12;GNG11;GNAI1
 hsa04080 Neuroactive ligand-receptor interaction 3.63E-06 P2RY14;NPY1R;APLNR;HTR5A;ADRA2A
Module2
 hsa04120 Ubiquitin mediated proteolysis 6.7E-07 NEDD4;CDC27;UBE2E2;TCEB1
 hsa05211 Renal cell carcinoma 0.035716 TCEB1
Module3
 hsa05200 Pathways in cancer 5.39E-12 CSF1R;JUN;FZD7;FZD6;PDGFA;WNT9A;FOS;FGF2;BMP4;FGF7;BMP2;IL6;COL4A4;FGF13
 hsa04550 Signaling pathways regulating pluripotency of stem cells 7.52E-09 BMP4;BMP2;ACVR1C;FZD7;FZD6;WNT9A;BMPR1B;FGF2
 hsa04390 Hippo signaling pathway 1.35E-08 BMP4;BMP2;FZD7;FZD6;WNT9A;BMPR1B;CTGF;BMP5
Module 4
 hsa05200 Pathways in cancer 1.73E-10 PLCB4;EDNRB;EGF;MMP1;ITGA2;F2R;CTNNB1;LPAR4;PTGS2
 hsa04015 Rap1 signaling pathway 8.32E-08 PLCB4;EGF;F2R;CTNNB1;LPAR4;THBS1
 hsa04072 Phospholipase D signaling pathway 4.31E-07 DNM3;PLCB4;EGF;F2R;LPAR4
  1. Top 3 terms were selected according to P-value when more than 3 terms enriched terms were identified in each category