Table 2 KEGG pathway enriched by differentially expressed genes in different modules
From: Differentially expressed genes between systemic sclerosis and rheumatoid arthritis
Term | Description | P-value | Genes |
|---|---|---|---|
Module1 | |||
 hsa04062 | Chemokine signaling pathway | 1.04E-08 | PPBP;CXCL13;GNG12;GNG11;CXCL5;GNAI1 |
 hsa04726 | Serotonergic synapse | 2.68E-06 | HTR5A;GNG12;GNG11;GNAI1 |
 hsa04080 | Neuroactive ligand-receptor interaction | 3.63E-06 | P2RY14;NPY1R;APLNR;HTR5A;ADRA2A |
Module2 | |||
 hsa04120 | Ubiquitin mediated proteolysis | 6.7E-07 | NEDD4;CDC27;UBE2E2;TCEB1 |
 hsa05211 | Renal cell carcinoma | 0.035716 | TCEB1 |
Module3 | |||
 hsa05200 | Pathways in cancer | 5.39E-12 | CSF1R;JUN;FZD7;FZD6;PDGFA;WNT9A;FOS;FGF2;BMP4;FGF7;BMP2;IL6;COL4A4;FGF13 |
 hsa04550 | Signaling pathways regulating pluripotency of stem cells | 7.52E-09 | BMP4;BMP2;ACVR1C;FZD7;FZD6;WNT9A;BMPR1B;FGF2 |
 hsa04390 | Hippo signaling pathway | 1.35E-08 | BMP4;BMP2;FZD7;FZD6;WNT9A;BMPR1B;CTGF;BMP5 |
Module 4 | |||
 hsa05200 | Pathways in cancer | 1.73E-10 | PLCB4;EDNRB;EGF;MMP1;ITGA2;F2R;CTNNB1;LPAR4;PTGS2 |
 hsa04015 | Rap1 signaling pathway | 8.32E-08 | PLCB4;EGF;F2R;CTNNB1;LPAR4;THBS1 |
 hsa04072 | Phospholipase D signaling pathway | 4.31E-07 | DNM3;PLCB4;EGF;F2R;LPAR4 |