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Fig. 6 | Hereditas

Fig. 6

From: The inhibition of miR-126 in cell migration and invasion of cervical cancer through regulating ZEB1

Fig. 6

MiR-126 suppressed MMP2 and MMP9 expression and inactivated JAK2/STAT3 signaling pathway by targeting ZEB1 in both SiHa and Hela cells. The effect of miR-126 on mRNA expression of a. ZEB1, b. MMP2 and c. MMP9 were evaluated by RT-qPCR. d Western blot was conducted to detected the protein levels of ZEB1, JAK2, p-JAK2, STAT3, p-STAT3, MMP2 and MMP9. GAPDH was used as the loading control. The relative expression of each protein was quantified. Data were presented as mean ± SEM. ** P < 0.01

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