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Table 2 GO ontology of differentially expressed genes of black and white horse skin

From: Regulatory pathway analysis of coat color genes in Mongolian horses

GO ontology

Cluster frequency

P value

DEG

%

Biological processes

 Lipid metabolic process

21

1.41

2.60E-05

 Lipid biosynthetic process

13

0.87

2.70E-05

 Cellular lipid metabolic process

16

1.07

5.74E-05

 Skeletal system development

12

0.80

1.15E-04

 Behavior

13

0.87

8.62E-04

 Phospholipid biosynthetic process

6

0.40

2.04E-03

 Tyrosine metabolic process

3

0.20

2.65E-03

 System development

34

2.28

2.84E-03

 Gycerolipid metabolic process

7

0.47

3.05E-03

 developmental process

42

2.81

3.71E-03

 Multicellular organismal development

39

2.61

4.03E-03

 Secondary metabolic process

5

0.33

5.13E-03

 Glycerolipid biosynthetic process

5

0.33

5.37E-03

 Anatomical structure development

35

2.34

5.56E-03

 Phospholipid metabolic process

7

0.47

6.62E-03

 Multicellular organismal process

52

3.48

6.63 E-03

 Response to wounding

12

0.80

6.97E-03

 Organ development

26

1.74

8.40E-03

 Organophosphate metabolic process

7

0.47

8.42E-03

 Carboxylic acid transport

6

0.40

9.57E-03

 Organic acid transport

6

0.40

9.84E-03

 Aromatic amino acid family metabolic process

3

0.20

0.0119

 Aromatic compound catabolic process

3

0.20

0.0131

 Regulation of biological quality

22

1.47

0.0169

 Cell adhesion

13

0.87

0.0201

 Amine transport

5

0.33

0.0202

 Biological adhesion

13

0.87

0.0203

 Oxoacid metabolic process

11

0.74

0.0246

 Carboxylic acid metabolic process

11

0.74

0.0246

 Organic acid metabolic process

11

0.74

0.0257

 Cellular ketone metabolic process

11

0.74

0.0276

 Vitamin metabolic process

4

0.27

0.0282

 Response to external stimulus

15

1.00

0.0300

 Tissue development

12

0.80

0.0321

 Locomotory behavior

7

0.47

0.0339

 Metal ion homeostasis

6

0.40

0.0346

 Anterior/posterior pattern formation

5

0.33

0.0349

 Chemical homeostasis

10

0.67

0.0365

 System process

21

1.41

0.0384

 Lipid transport

5

0.33

0.0389

 Cation homeostasis

7

0.47

0.0404

 Sensory perception of light stimulus

6

0.40

0.0418

 Visual perception

6

0.40

0.0418

 Tyrosine catabolic process

2

0.13

0.0431

 Regulation of very-low-density lipoprotein particle remodeling

2

0.13

0.0431

 Amino acid transport

4

0.27

0.0448

 Lipid localization

5

0.33

0.0496

Cellular component

 Extracellular region

39

2.61

8.82E-07

 Extracellular region part

23

1.54

1.63E-05

 Extracellular space

17

1.14

2.10E-04

 Endoplasmic reticulum

17

1.14

6.86E-03

 High-density lipoprotein particle

3

0.20

0.0186

 Protein-lipid complex

3

0.20

0.0350

 Plasma lipoprotein particle

3

0.20

0.0350

Molecular function

 O-acyltransferase activity

7

0.47

7.67E-07

 Acyltransferase activity

9

0.60

2.76E-04

 Transferase activity, transferring acyl groups other than amino-acyl groups

9

0.60

2.95E-04

 Transferase activity, transferring acyl groups

9

0.60

3.83E-04

 Receptor binding

17

1.14

2.77 E-03

 Cytokine activity

7

0.47

5.80E-03

 Hemoglobin binding

2

0.13

0.0248

 Protein dimerization activity

10

0.67

0.0371

 Carboxylesterase activity

4

0.27

0.0460

  1. % = DGE/BGDGE × 100%; DEG represents the number of differentially expressed genes annotated to each GO ontology. BGDEG represents the number of all background differentially expressed genes annotated to each GO ontology