Table 2 Leptin-induced genes associated with OA in this study
Accession number | Gene symbol | Description | Fold change |
|---|---|---|---|
NM_133523 | MMP3 | Rattus norvegicus matrix metallopeptidase 3 | 2.87 |
NM_031055 | MMP9 | Rattus norvegicus matrix metallopeptidase 9 | 2.09 |
NM_133530 | MMP13 | Rattus norvegicus matrix metallopeptidase 13 | 2.06 |
NM_031512 | IL-1β | Rattus norvegicus interleukin 1 beta | 3.01 |
NM_012589 | IL-6 | Rattus norvegicus interleukin 6 | 4.66 |
NM_013110 | IL-7 | Rattus norvegicus interleukin 7 | 2.86 |
NM_012854 | IL-10 | Rattus norvegicus interleukin 10 | 3.43 |
NM_013104 | IGFBP6 | Rattus norvegicus insulin-like growth factor binding protein 6 | 8.28 |
NM_171988 | BCL2L11 | Rattus norvegicus BCL2-like 11 (apoptosis facilitator) | 2.85 |
NM_031560 | CTSK | Rattus norvegicus cathepsin K | 3.61 |
NM_133416 | SYK | Rattus norvegicus spleen tyrosine kinase | 6.11 |
AF279918 | RGS2 | regulator of G-protein signaling 2 | 2.14 |
NM_001137622 | ADAMTS2 | Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1 motif, 2 | 2.77 |
M12199 | COL1A1 | Rat alpha-1 type I collagen mRNA | 4.01 |
NM_057149 | TNFSF11 | Rattus norvegicus tumor necrosis factor (ligand) superfamily, member 11 | 2.88 |
NM_001109524 | CHML | Rattus norvegicus choroideremia-like (Rab escort protein 2) | −2.32 |
NM_001105980 | NVL | Rattus norvegicus nuclear VCP-like | −2.54 |
NM_001100527 | FRZB | Rattus norvegicus frizzled-related protein | −2.76 |