Adaptation of human skin color in various populations

Hereditas

Table 1 A summary of candidate genes of human adaptation on pigmentation

Gene	SNP	Skin color	Hair color	Eye color	References
APBA2	rs4424881	√			[68]
ASIP	rs6058017	√		√	[71, 72, 74, 118]
ASIP	rs4911442	√		√	[40, 118]
DCT	rs1325611	√			[49]
	rs1407995	√			[40, 49, 74]
	rs9516418	√			[49]
	rs3782974	√			[50]
	rs2031526	√			[38]
GRM5	rs10831469	√			[68]
HERC2	rs79097182		√		[60]
IRF4	rs12203592	√	√		[40, 118]
IRF4	rs1540771		√		[60, 118]
KITLG	rs1881227	√			[56, 119]
	rs642742	√			[61, 118]
	rs12821256		√		[40, 60, 118]
MC1R	rs885479	√	√		[40, 74, 118, 119]
	rs1805005	√	√		[29, 74, 118, 120]
	rs1805006	√	√		[74, 118]
	rs1805007	√	√		[57, 74, 118, 121]
	rs1805008	√	√		[57, 74, 118]
	rs1805009		√		[118]
	rs2228479	√	√		[74, 107, 118]
	rs2353688		√		[60]
	rs146972365		√		[60]
	rs8063160		√		[60]
	rs11547464	√		√	[118]
	rs1110400	√	√		[118]
OCA2	rs12913832	√		√	[23, 40, 68, 118]
	rs1800404	√			[48]
	rs1800407	√		√	[118]
	rs1800414	√		√	[40, 47, 50, 118, 122]
	rs74653330	√			[40, 48]
	rs150335311	√			[48]
	rs1448484	√			[50]
	rs1667394	√			[57]
SLC24A4	rs12896399	√	√	√	[57, 118]
SLC24A4	rs8014907		√		[60]
SLC24A5	rs1426654	√			[17, 23, 40, 61, 68, 72, 75, 118]
SLC24A5	rs2470102	√		√	[68]
SLC45A2	rs16891982	√			[17, 18, 21, 23, 27, 40, 50, 61, 112, 118]
	rs26722	√			[18, 27, 118]
	rs11568737	√			[48]
	rs35395	√			[68]
TPCN2	rs72930659		√		[60]
	rs35264875	√			[118]
	rs3829241	√			[118]
TYR	rs1042602	√			[40, 57, 68, 118]
	rs1393350	√			[57]
	rs13312741	√			[48]
	rs10831469	√			[68]
	rs1126809	√			[40, 118]
	rs1800422	√			[118]
TYRP1	rs2733832	√		√	[49, 118]
	rs2733831	√			[61]
	rs10809814	√			[49]
	rs2762464	√			[50]
	rs1408799	√		√	[40, 118]