The Trp719Arg polymorphism of the KIF6 gene and coronary heart disease risk: systematic review and meta-analysis

Hereditas

Table 1 Descriptive characteristics of the association studies on the Trp719Arg polymorphism of the KIF6 gene and CHD included in the meta-analysis and systematic review

Author	Year	Country	Ethnicity	Number		Diagnosis	Mean age
				Cases	Control		Cases	Control
Berglund, G. [17]	1993	Sweden	Caucasians	86	99	MI	48.5	48.7
Vartiainen, E. [18]	2000	Finland	Caucasians	167	172	MI	47.1	47.1
Senti, M. [19]	2001	Spain	Caucasians	312	317	MI	45.9	46.0
Yusuf, S. [20]	2004	Bangladesh, Sri Lanka, Pakistan, others.	Asians	1092	1187	MI	51.4	49.8
Low, A. F. [21]	2005	USA	Caucasians	204	260	MI	47.0	53.8
Helgadottir, A. [22]	2007	USA	Caucasians	875	447	CAD	48.9	59.8
Helgadottir, A. [22]	2007	USA	Caucasians	933	468	CAD	52.7	61.7
Samani, N. J. [23]	2007	Germany	Caucasians	1126	1277	MI	51.3	51.2
Samani, N. J. [23]	2007	Germany	Caucasians	722	1643	MI	50.2	62.5
Meng, W. [24]	2007	Northern Ireland	Caucasians	482	622	MI	46.0	55.2
Iakoubova, O. [14]	2008	USA	Caucasians	276	519	MI	56.4	56.2
Meiner, V. [25]	2008	USA	Caucasians	505	559	MI	46.0	45.2
Serre, D. [26]	2008	Several	Several	789	859	MI	61.6	61.2
Morgan, T. M. [27]	2008	USA	Caucasians	807	637	MI	61.5	60.7
Assimes, T. L. [28]	2008	USA	Caucasians	505	514	CAD	45.4	45.6
Vennemann, M. M. [29]	2008	Germany	Caucasians	793	1121	MI	52.2	52.6
Sutton, B. S. [30]	2008	USA	Caucasians	1575	970	MI	28.9	52.4
Martinelli, W. [31]	2008	Italy	Caucasians	1106	383	CAD	61.4	58.0
Herrera-Galeano, J. E. [32]	2008	USA	Caucasians	378	2652	CAD	46.9	47.2
Stewart, A. F. [33]	2009	Canada	Caucasians	1540	1455	MI	49.0	75
Luke, M. M. [34]	2009	Austria	Caucasians	505	782	CAD	66.0	58.8
Bare, L. A. [13]	2010	Costa Rica	Latin-Americans	1987	2147	MI	58.3	58.3
Wu, G. [16]	2012	China	Asians	356	568	CAD	64.9	60.3
Wu, G. [16]	2012	China	Asians	114	568	MI	64.9	60.3
Peng, P. [15]	2012	China	Asians	289	522	CAD	-	-
Wu, G. [35]	2014	China	Asians	288	346	CAD	63.8	60.2

ISSN: 1601-5223