Table 3 Molecular docking score of seven high-peak compounds of HH with NF-κB, NLRP3, ASC, and Caspase-1
Compounds | Binding Energy (kcal/mol) | |||
|---|---|---|---|---|
NF-κB NLRP3 ASC Caspase-1 | ||||
Dulcitol | -5.50 | -4.80 | -4.40 | -3.0 |
Coptisine | -8.90 | -7.10 | -8.50 | -6.0 |
Berberine | -9.70 | -7.80 | -7.50 | -5.20 |
Epiberberine | -8.60 | -6.90 | -7.10 | -5.40 |
Palmatine | -8.70 | -6.70 | -6.80 | -4.90 |
Lovastatin | -7.10 | -5.70 | -6.70 | -5.10 |
Quercetin | -8.80 | -7.40 | -7.30 | -5.40 |